Natural Killer Cells
Natural Killer Cells
Natural Killer Cells (NK Cells), pronounced as /ˈnætʃərəl ˈkɪlər sɛlz/, are a type of Cytotoxic Lymphocyte crucial to the Innate Immune System. The term "Natural Killer Cell" is derived from the cell's natural ability to kill Cancer Cells and Virus-infected Cells without prior sensitization to a specific Antigen.
Function
Natural Killer Cells play a significant role in the rejection of Tumors and cells infected by Viruses. They kill cells by releasing small cytoplasmic granules of proteins called Perforin and Granzyme that cause the target cell to die by Apoptosis (cell death).
Classification
Natural Killer Cells are classified as group I Innate Lymphoid Cells (ILCs) due to their unique ability to respond quickly to a wide variety of pathological challenges.
Interaction with Other Cells
Natural Killer Cells interact with a variety of other cells in the body, including Dendritic Cells, Macrophages, T Cells, and other Lymphocytes. These interactions are crucial for the regulation of Immune Responses and Inflammation.
Related Terms
External links
- Medical encyclopedia article on Natural Killer Cells
- Wikipedia's article - Natural Killer Cells
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