Nilestriol
Nilestriol
Nilestriol (pronounced: nɪˈlɛstriːɒl) is a synthetic, steroidal estrogen that is used in hormone replacement therapy for menopausal symptoms and in the treatment of various gynecological disorders. It is also known as 17α-ethynyl-3-methoxy-19-nor-17β-pregna-1,3,5(10)-trien-20-yne.
Etymology
The term "Nilestriol" is derived from the chemical structure of the compound. The prefix "Nile" is derived from the Latin word "nil", meaning "nothing", referring to the absence of a carbon atom at the 19th position in the steroid structure. The suffix "striol" is a combination of "estradiol", a natural estrogen, and "triol", indicating the presence of three hydroxyl groups in the molecule.
Usage
Nilestriol is primarily used in the treatment of menopausal symptoms such as hot flashes, night sweats, mood swings, and vaginal dryness. It is also used in the treatment of osteoporosis, a condition that weakens bones and makes them more prone to fractures, which is common in postmenopausal women. In addition, it is used in the treatment of certain gynecological disorders such as abnormal uterine bleeding and endometriosis.
Related Terms
- Estrogen: A group of hormones that play an essential role in the growth and development of female sexual characteristics and the reproductive process.
- Hormone replacement therapy: A treatment used to supplement the body with either estrogen alone or estrogen and progesterone in combination during and after menopause.
- Osteoporosis: A condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones.
- Endometriosis: A disorder in which tissue similar to the tissue that forms the lining of the uterus grows outside of the uterine cavity.
External links
- Medical encyclopedia article on Nilestriol
- Wikipedia's article - Nilestriol
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