Ophanin
Ophanin
Ophanin (/ɒfənɪn/) is a peptide that was first isolated from the venom of the king cobra (Ophiophagus hannah). It is a potent blocker of the tetrodotoxin-sensitive voltage-gated sodium channels in the nervous system.
Etymology
The term "Ophanin" is derived from the genus name of the king cobra, Ophiophagus, and the suffix "-in", which is commonly used in the nomenclature of proteins and peptides.
Function
Ophanin acts by blocking the tetrodotoxin-sensitive voltage-gated sodium channels, which play a crucial role in the generation and propagation of action potentials in neurons. By blocking these channels, Ophanin can inhibit the transmission of nerve impulses, leading to a variety of effects such as pain relief and muscle relaxation.
Related Terms
- Peptide: A short chain of amino acids, the building blocks of proteins.
- Ophiophagus hannah: The scientific name for the king cobra, a venomous snake species found in parts of Asia.
- Tetrodotoxin: A potent neurotoxin that is known to block voltage-gated sodium channels.
- Sodium channels: Protein channels in the cell membrane that allow sodium ions to pass through.
- Nervous system: The complex network of nerves and cells that transmit signals between different parts of the body.
External links
- Medical encyclopedia article on Ophanin
- Wikipedia's article - Ophanin
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