PDE5 inhibitor
PDE5 inhibitor
A PDE5 inhibitor is a type of drug that is primarily used in the treatment of certain medical conditions such as erectile dysfunction and pulmonary hypertension.
Pronunciation
PDE5 inhibitor is pronounced as "P-D-E-Five Inhibitor".
Etymology
The term "PDE5 inhibitor" is derived from the full scientific name, Phosphodiesterase type 5 inhibitor. Phosphodiesterase is an enzyme that promotes the breakdown of cGMP, a substance that relaxes smooth muscle cells. The number 5 refers to the specific type of phosphodiesterase targeted by these drugs.
Usage
PDE5 inhibitors work by blocking the action of phosphodiesterase type 5, thus preventing the breakdown of cGMP. This leads to an increase in blood flow to certain areas of the body, which can help to alleviate symptoms of conditions such as erectile dysfunction and pulmonary hypertension.
Related Terms
- Erectile Dysfunction: A condition characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse.
- Pulmonary Hypertension: A type of high blood pressure that affects the arteries in the lungs and the right side of the heart.
- Cyclic Guanosine Monophosphate: A substance that relaxes smooth muscle cells, allowing for increased blood flow.
- Phosphodiesterase: An enzyme that promotes the breakdown of cGMP.
See Also
External links
- Medical encyclopedia article on PDE5 inhibitor
- Wikipedia's article - PDE5 inhibitor
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