PLX4032
| PLX4032 | |
|---|---|
| Term | PLX4032 |
| Short definition | PLX4032 - A drug used to treat Erdheim-Chester disease (a very rare form of histiocytosis) and advanced melanoma, which have a specific mutation (change) in the BRAF gene. It is also being studied in the treatment of other types of cancer. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
PLX4032 - A drug used to treat Erdheim-Chester disease (a very rare form of histiocytosis) and advanced melanoma, which have a specific mutation (change) in the BRAF gene. It is also being studied in the treatment of other types of cancer. PLX4032 blocks certain proteins made by the mutated BRAF gene, which may help prevent cancer cells from growing. It's a kind of kinase inhibitor. Also known as BRAF (V600E) kinase inhibitor RO5185426, RG7204, vemurafenib and Zelboraf
External links
- Medical encyclopedia article on PLX4032
- Wikipedia's article - PLX4032
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