Pappenheimer bodies
Pappenheimer bodies
Pappenheimer bodies (/pæpənˌhaɪmər ˈbɒdiz/), also known as siderotic granules, are abnormal granules of iron found inside red blood cells. They are named after American pathologist James Pappenheimer, who first described them in 1945.
Etymology
The term "Pappenheimer bodies" is derived from the name of James Pappenheimer, an American pathologist who first identified these iron granules. The term "siderotic granules" comes from the Greek word "sideros", meaning iron, and the suffix "-otic", which refers to a condition or state.
Description
Pappenheimer bodies are small, irregular, basophilic granules that appear within the cytoplasm of red blood cells. They are composed of iron, and are often associated with conditions that cause excess iron in the body, such as sideroblastic anemia and hemochromatosis.
Related Terms
- Anemia: A condition characterized by a deficiency of red blood cells or of hemoglobin in the blood.
- Hemochromatosis: A hereditary disease characterized by improper processing by the body of dietary iron which leads to iron overload.
- Sideroblastic anemia: A group of blood disorders characterized by an inability of the bone marrow to produce normal red blood cells.
- Pathology: The science of the causes and effects of diseases, especially the branch of medicine that deals with the laboratory examination of samples of body tissue for diagnostic or forensic purposes.
See Also
External links
- Medical encyclopedia article on Pappenheimer bodies
- Wikipedia's article - Pappenheimer bodies
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