Peginesatide
Peginesatide
Peginesatide (pronounced as peg-in-es-a-tide) is a synthetic, peptide-based erythropoiesis-stimulating agent (ESA). It is used to treat anemia associated with chronic kidney disease in adult patients on dialysis.
Etymology
The name "Peginesatide" is derived from the combination of "PEG", an acronym for polyethylene glycol, and "inesatide", which is a synthetic peptide. The "PEG" part of the name refers to the fact that the drug is a PEGylated compound, meaning it has been modified with polyethylene glycol to improve its stability and half-life.
Mechanism of Action
Peginesatide works by stimulating the bone marrow to produce more red blood cells, mimicking the effect of the natural hormone erythropoietin. This helps to alleviate the symptoms of anemia, such as fatigue and weakness.
Related Terms
- Erythropoiesis-stimulating agent (ESA): A type of drug that stimulates the production of red blood cells.
- Anemia: A condition characterized by a deficiency of red blood cells or of hemoglobin in the blood.
- Kidney disease: A condition in which the kidneys are damaged and can't filter blood as well as they should.
- Dialysis: A treatment that filters and purifies the blood using a machine. This helps keep your body in balance when the kidneys can’t perform this function.
- Erythropoietin: A hormone that stimulates the production of red blood cells.
External links
- Medical encyclopedia article on Peginesatide
- Wikipedia's article - Peginesatide
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