Posterior polymorphous corneal dystrophy

Posterior Polymorphous Corneal Dystrophy (pronunciation: poh-STEER-ee-or pol-ee-MOR-fus KOR-nee-al dis-TROH-fee) is a rare, genetic eye disorder that affects the cornea. The term is derived from the Latin posterior (meaning "back"), polymorphous (meaning "having many forms"), corneal (pertaining to the cornea), and dystrophy (meaning "disorder involving a body part").

Definition

Posterior Polymorphous Corneal Dystrophy (PPCD) is a condition characterized by changes in the endothelium, the innermost layer of the cornea. These changes can lead to vision problems, including blurred vision and glare.

Symptoms

Symptoms of PPCD can vary greatly among affected individuals. Some people may have no symptoms, while others may experience significant vision problems. Common symptoms include blurred vision, glare, and sensitivity to light.

Causes

PPCD is a genetic disorder, which means it is caused by changes (mutations) in genes. The condition is usually inherited in an autosomal dominant manner, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

Diagnosis

Diagnosis of PPCD is based on a thorough eye examination, including a special test called a slit lamp examination. Genetic testing may also be used to confirm the diagnosis.

Treatment

Treatment for PPCD may include eye drops to reduce swelling and discomfort. In severe cases, a corneal transplant may be necessary.

Related Terms

External links

Medical encyclopedia article on Posterior polymorphous corneal dystrophy
Wikipedia's article - Posterior polymorphous corneal dystrophy

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