Primary Biliary Cirrhosis
Primary Biliary Cirrhosis (pronunciation: pri-ma-ry bil-i-ary sir-roh-sis) is a chronic disease that affects the liver. It is characterized by the slow, progressive destruction of the small bile ducts within the liver. When these ducts are damaged, bile can back up in the liver and lead to cirrhosis, a condition that can lead to liver failure.
Etymology
The term "Primary Biliary Cirrhosis" is derived from the Latin words "primus" meaning first, "bilis" meaning bile, and "cirrhosis" meaning yellowish. This refers to the primary (first) damage occurring in the bile ducts, leading to a yellowish discoloration of the liver due to cirrhosis.
Symptoms
The symptoms of Primary Biliary Cirrhosis can vary greatly from person to person. Some people may have no symptoms at all, while others may experience fatigue, itching, and yellowing of the skin and eyes (jaundice). As the disease progresses, it can lead to complications such as ascites, varices, and hepatic encephalopathy.
Diagnosis
Diagnosis of Primary Biliary Cirrhosis is typically made through a combination of blood tests, imaging studies, and sometimes a liver biopsy. The presence of certain antibodies in the blood can be indicative of the disease.
Treatment
While there is no cure for Primary Biliary Cirrhosis, treatments are available to help manage symptoms and slow the progression of the disease. These may include medications to help reduce bile buildup in the liver, such as ursodeoxycholic acid, and treatments for specific symptoms such as itching and fatigue.
Related Terms
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