From WikiMD
Jump to navigation Jump to search

Information about Procainamide

Procainamide is an oral antiarrhythmic agent that has been in wide use for more than 60 years.

Liver safety of Procainamide

Long term procainamide therapy is known to induce hypersensitivity reactions, autoantibody formation and a lupus-like syndrome but is a rare cause of clinically apparent acute liver injury.

Mechanism of action of Procainamide

Procainamide (proe kane' a mide) is an analogue of the local anesthetic procaine and has electrophysiological effects that resemble quinidine. Procainamide appears to act by blocking open sodium channels and outward potassium channels. As a consequence, it decreases cardiac automaticity, increases refractory periods and slows conduction.

FDA approval information for Procainamide

Procainamide was approved for use in the United States in 1950, and current indications include suppression of symptomatic premature ventricular contractions and life threatening ventricular tachycardia, as well as maintenance of normal sinus rhythm after conversion of atrial fibrillation or flutter. Because of its safety profile, procainamide is now rare used.

Dosage and administration for Procainamide

Procainamide is available in capsules and tablets of 250, 375 and 500 mg generically as well as under the brand name Pronestyl; it is also available as extended release forms of 250, 500, 750 and 1,000 mg under the brand name Procanbid. The usual maintenance dose in adults is 500 to 1000 mg every 4 to 6 hours.

Side effects of Procainamide

The most common side effects include headache, nervousness, anxiety, nausea, decreased appetite, palpitations and disturbed sleep.

List of antiarrhythmic agents:

Cost and Coupons - Procainamide

Reviews for Procainamide

This article is a stub. YOU can help Wikimd by expanding it!

Articles on Procainamide


Learn more about Procainamide

Help WikiMD

Find something you can improve? Join WikiMD as an an editor and help improve this page or others.

Apple bitten.svg

WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="">Procainamide</a>

  • Individual results may vary for weight loss from our sponsors.