Propylthiouracil

Propylthiouracil (pronounced pro-pil-thy-oh-YOU-rah-sil) is a medication primarily used to treat hyperthyroidism, a condition characterized by an overactive thyroid gland.

Etymology

The term "Propylthiouracil" is derived from its chemical structure. It contains a propyl group (a three-carbon chain), a sulfur atom (thio), and a uracil base, which is a component of RNA.

Usage

Propylthiouracil works by inhibiting the enzyme thyroid peroxidase, which plays a crucial role in the production of thyroid hormones, thyroxine (T4) and triiodothyronine (T3). By blocking this enzyme, propylthiouracil reduces the amount of thyroid hormones produced by the thyroid gland, thereby alleviating the symptoms of hyperthyroidism.

Related Terms

Hyperthyroidism: A condition in which the thyroid gland produces too much thyroid hormone.
Thyroid gland: A butterfly-shaped gland located in the neck that produces thyroid hormones.
Thyroid peroxidase: An enzyme that plays a crucial role in the production of thyroid hormones.
Thyroxine (T4): A thyroid hormone that plays a key role in regulating the body's metabolism.
Triiodothyronine (T3): Another thyroid hormone that plays a key role in regulating the body's metabolism.

Side Effects

Like all medications, propylthiouracil can cause side effects. The most common ones include skin rash, nausea, vomiting, and joint pain. In rare cases, it can cause severe liver damage. Therefore, it's important for patients taking propylthiouracil to have regular blood tests to monitor their liver function.

External links

Medical encyclopedia article on Propylthiouracil
Wikipedia's article - Propylthiouracil

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Propylthiouracil