Prucalopride
Prucalopride
Prucalopride (pronounced proo-KAL-oh-pride) is a medication used in the treatment of chronic constipation. It is classified as a selective, high affinity serotonin (5-HT4) receptor agonist.
Etymology
The name "Prucalopride" is derived from its chemical structure. The "Pru" part of the name is short for propyl, referring to the propyl group in its chemical structure. The "calo" part of the name is derived from the Latin word "calor", meaning heat, which refers to the drug's ability to stimulate the gastrointestinal tract. The "pride" part of the name is a common suffix used in drug nomenclature, often used for drugs that interact with the serotonin system.
Usage
Prucalopride is used to treat chronic constipation in adults for whom laxatives have not provided adequate relief. It works by stimulating the muscles in the wall of the gut, helping to increase the movement of stools through the bowel.
Related Terms
- Serotonin: A neurotransmitter that sends signals in the brain. It is involved in many functions, including mood, appetite, and sleep.
- Gastrointestinal tract: The series of organs in the digestive system through which food passes, nutrients are extracted, and waste is eliminated.
- Constipation: A common condition that affects people of all ages. It can mean that you're not passing stools regularly or you're unable to completely empty your bowel.
Side Effects
Common side effects of Prucalopride include headache, abdominal pain, nausea, diarrhea, and fatigue. If these side effects persist or worsen, patients are advised to contact their healthcare provider.
See Also
- 5-HT4 receptor: A subtype of the serotonin receptor that Prucalopride has a high affinity for.
- Laxative: A type of medicine that helps to relieve constipation.
External links
- Medical encyclopedia article on Prucalopride
- Wikipedia's article - Prucalopride
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