Pyostomatitis vegetans
Pyostomatitis vegetans (pronunciation: py-o-sto-ma-ti-tis ve-ge-tans) is a rare, chronic, and recurrent inflammatory disease that primarily affects the oral cavity. It is often associated with inflammatory bowel disease (IBD), particularly ulcerative colitis and, to a lesser extent, Crohn's disease.
Etymology
The term "Pyostomatitis vegetans" is derived from the Greek words "pyon" (pus), "stoma" (mouth), and "vegetans" (growing). It was first described in 1949 by McCarthy and colleagues.
Clinical Presentation
Patients with pyostomatitis vegetans often present with multiple, small, yellowish-white pustules in the mouth. These pustules may coalesce to form snail-track ulcers. Other symptoms may include erythema, edema, and a burning sensation in the mouth.
Diagnosis
Diagnosis of pyostomatitis vegetans is primarily based on clinical presentation and histopathological findings. The presence of eosinophilic microabscesses and acantholytic cells in the oral mucosa are characteristic histological features.
Treatment
Treatment of pyostomatitis vegetans often involves managing the underlying inflammatory bowel disease. Topical corticosteroids are commonly used to manage oral symptoms. In severe cases, systemic therapy with corticosteroids, dapsone, or other immunosuppressive agents may be required.
Prognosis
The prognosis of pyostomatitis vegetans is generally good with appropriate treatment. However, the disease often follows a chronic and recurrent course, and long-term monitoring is necessary.
See Also
External links
- Medical encyclopedia article on Pyostomatitis vegetans
- Wikipedia's article - Pyostomatitis vegetans
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