Randomized Controlled Trial
Randomized Controlled Trial
A Randomized Controlled Trial (pronounced: /ˈrændəˌmaɪzd kənˈtroʊld ˈtraɪəl/), often abbreviated as RCT, is a type of Scientific experiment specifically designed to reduce bias when testing the effectiveness of new treatments. The RCT is often considered the gold standard for a Clinical trial.
Etymology
The term "Randomized Controlled Trial" originates from the process of randomization used in the trial. The word "randomize" (from the Latin randomis, meaning "by chance") refers to the method of assigning participants to different groups without any systematic bias. "Controlled" refers to the use of a control group that receives a placebo or standard treatment, and "trial" refers to the experimental testing process.
Process
In a Randomized Controlled Trial, participants are randomly assigned to either the experimental group or the control group. The experimental group receives the treatment under investigation, while the control group receives a Placebo or the standard treatment. The outcomes of both groups are then compared to determine the effectiveness of the new treatment.
Related Terms
- Blinding (masking): A technique used in RCTs to prevent bias by ensuring that the participants and researchers do not know which group the participants are in.
- Placebo: A substance with no therapeutic effect used as a control in testing new drugs.
- Clinical trial: A research investigation involving human subjects designed to answer specific questions about biomedical or behavioral interventions.
See Also
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