Rapid plasma reagin

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Rapid plasma reagin

Rapid plasma reagin (pronounced: /ˈræpɪd ˈplæzmə riˈædʒɪn/), often abbreviated as RPR, is a type of blood test used to screen for syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. The term "reagin" refers to an antibody-like substance present in the blood of individuals with syphilis.

Etymology

The term "rapid plasma reagin" is derived from the speed of the test (rapid), the type of sample used (plasma), and the type of reaction observed (reagin).

Procedure

The RPR test is performed by mixing a sample of the patient's blood with a specific antigen. If reagin antibodies are present in the blood, they will bind to the antigen, causing visible clumping or flocculation. This result is considered positive and indicates a likely infection with syphilis.

Related Terms

  • VDRL test: Another type of blood test used to detect syphilis. It is similar to the RPR test but is more complex and requires a longer time to perform.
  • Treponema pallidum particle agglutination assay (TPPA): A more specific test for syphilis that can confirm a positive RPR or VDRL result.
  • Antibody: A protein produced by the immune system that recognizes and helps fight infections.
  • Antigen: A substance that triggers an immune response, leading to the production of antibodies.

See Also

External links

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