Restriction fragment
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Restriction Fragment
Restriction Fragment (pronunciation: /rɪˈstrɪkʃən ˈfrægmənt/) is a term used in molecular biology to describe a DNA fragment resulting from the cutting of a DNA molecule by a restriction enzyme.
Etymology
The term "restriction fragment" is derived from the function of the restriction enzymes that create them. These enzymes "restrict" the DNA molecule by cutting it at specific sites, thus producing "fragments".
Related Terms
- Restriction Enzyme: An enzyme that cuts DNA at specific recognition nucleotide sequences known as restriction sites.
- DNA: Deoxyribonucleic acid, a self-replicating material which is present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information.
- Molecular Biology: The branch of biology that deals with the structure and function of the macromolecules (e.g. proteins and nucleic acids) essential to life.
- Nucleotide Sequence: The order of nucleotides in a DNA or RNA molecule, or the order of amino acids in a protein molecule.
- Restriction Sites: Locations on a DNA molecule containing specific sequences of nucleotides, which are recognized as cut sites by restriction enzymes.
See Also
External links
- Medical encyclopedia article on Restriction fragment
- Wikipedia's article - Restriction fragment
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