SOS box
SOS box
SOS box (pronounced: /ɛs oʊ ɛs bɒks/) is a genetic element found in the DNA of bacteria and some viruses. It is a part of the SOS response system, which is a global response to DNA damage. The SOS box is a sequence of DNA that is recognized and bound by the LexA repressor protein. When DNA damage occurs, the LexA repressor is inactivated, allowing transcription of the SOS genes.
Etymology
The term "SOS box" is derived from the SOS response system in which it plays a crucial role. The SOS response was named for the international distress signal "SOS" in Morse code, reflecting the system's role in responding to DNA damage, a form of cellular distress.
Related Terms
- SOS response: A global response to DNA damage in bacteria and some viruses, involving a set of genes that are transcribed in response to DNA damage.
- LexA: A repressor protein that binds to the SOS box and prevents transcription of the SOS genes under normal conditions.
- DNA damage: Changes to the chemical structure of DNA, which can be caused by various factors and can lead to mutations if not repaired.
- Transcription (genetics): The process of copying a segment of DNA into RNA, which is the first step in gene expression.
External links
- Medical encyclopedia article on SOS box
- Wikipedia's article - SOS box
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