STAT3
STAT3
STAT3 (pronounced "stat three"), also known as Signal Transducer and Activator of Transcription 3, is a protein that in humans is encoded by the STAT3 gene.
Pronunciation
- STAT3: /stæt θri:/
Etymology
The term STAT3 is an abbreviation of Signal Transducer and Activator of Transcription 3. The name reflects the protein's role in cell signaling and gene expression.
Function
STAT3 is a member of the STAT protein family. These proteins are critical for mediating responses to cytokines and growth factors. Upon cytokine receptor activation, STAT3 becomes phosphorylated, dimerizes, and translocates to the cell nucleus, where it acts as a transcription factor.
Related Terms
- STAT protein family
- Cytokines
- Growth factors
- Cytokine receptors
- Phosphorylation
- Cell nucleus
- Transcription factors
See Also
External links
- Medical encyclopedia article on STAT3
- Wikipedia's article - STAT3
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