Solvent detergent plasma
Solvent Detergent Plasma
Solvent Detergent Plasma (pronunciation: sɒlvənt dɪˈtɜːdʒənt ˈplazmə) is a type of plasma product used in medicine and transfusion therapy. It is treated with a solvent detergent process to inactivate viruses.
Etymology
The term "Solvent Detergent Plasma" is derived from the process used to treat the plasma. The word "solvent" (from Latin solvō, "loosen, untie, solve") refers to the substance, usually a liquid, that can dissolve another substance. "Detergent" (from Latin dētergēns, present participle of dētergēre, "to wipe away") is a type of cleaning agent. "Plasma" (from Ancient Greek πλάσμα, plasma, "something molded") is the liquid component of blood in which the blood cells are suspended.
Process
The solvent detergent process involves treating the plasma with a mixture of tri(n-butyl)phosphate (TNBP) and Triton X-100, a nonionic surfactant. This treatment inactivates enveloped viruses by disrupting their lipid envelopes. The solvent detergent plasma is then filtered to remove the detergent and the solvent.
Use in Medicine
Solvent detergent plasma is used in transfusion therapy as a safer alternative to fresh frozen plasma. It is used to treat patients with coagulation disorders, bleeding disorders, and other conditions that require plasma transfusion.
Related Terms
- Plasma (blood)
- Transfusion therapy
- Coagulation
- Bleeding disorder
- Virus
- Surfactant
- Tri(n-butyl)phosphate
- Triton X-100
External links
- Medical encyclopedia article on Solvent detergent plasma
- Wikipedia's article - Solvent detergent plasma
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