Stria terminalis

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Stria Terminalis

The Stria Terminalis (/ˈstraɪə tɜːrˈmɪnəlɪs/; from Latin, stria meaning "groove" and terminalis meaning "pertaining to a boundary or end") is a structure in the brain consisting of a band of fibers running along the lateral margin of the ventricle of the brain.

Anatomy

The Stria Terminalis begins in the region of the amygdala, an almond-shaped set of neurons located deep within the brain's medial temporal lobe, and follows a C-shaped path along the thalamus to end in the hypothalamus. It forms the superior boundary of the fornix, a C-shaped bundle of nerve fibers in the brain that carries signals from the hippocampus to the mammillary bodies and then to the anterior nuclei of thalamus.

Function

The Stria Terminalis is involved in the regulation of the body's response to stress, the regulation of circadian rhythms, and the process of memory formation. It is also involved in the modulation of anxiety and fear responses, and plays a role in the neurobiology of social behavior.

Clinical Significance

Abnormalities in the Stria Terminalis have been implicated in a number of neurological and psychiatric disorders, including anxiety disorders, post-traumatic stress disorder (PTSD), and Alzheimer's disease.

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