Structural Biology

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Structural Biology

Structural Biology (pronunciation: /ˈstrʌktʃərəl baɪˈɒlədʒi/) is a branch of biology that involves the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their function.

Etymology

The term "Structural Biology" is derived from the English words "structure" and "biology". "Structure" (from Latin structura) refers to the arrangement and interrelation of parts in a complex entity, and "biology" (from Greek bios, life, and -logia, study of) is the scientific study of life and living organisms.

Related Terms

  • Biochemistry: The branch of science concerned with the chemical and physicochemical processes and substances that occur within living organisms.
  • Molecular Biology: The branch of biology that deals with the structure and function of the macromolecules essential to life.
  • Biophysics: An interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena.
  • Protein Structure: The three-dimensional arrangement of atoms in an amino acid-chain molecule.
  • Nucleic Acid Structure: The structure of nucleic acids which includes DNA and RNA.
  • Crystallography: The science that examines the arrangement of atoms in crystalline solids.
  • NMR Spectroscopy: A research technique that exploits the magnetic properties of certain atomic nuclei to determine physical and chemical properties of atoms or the molecules in which they are contained.
  • Cryo-Electron Microscopy: A form of transmission electron microscopy where the sample is studied at cryogenic temperatures.

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