Structural domain

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Structural domain

A structural domain is a component of a protein that maintains a stable structure independently of the rest of the protein. Structural domains are units of protein structure that are capable of folding autonomously.

Pronunciation

Struc·tur·al do·main /ˈstrʌktʃərəl dəˈmeɪn/

Etymology

The term "structural domain" is derived from the English words "structure" and "domain". "Structure" comes from the Latin word "structura" meaning "a fitting together, building". "Domain" comes from the French word "domaine", which means "domain, estate."

Related terms

  • Protein domain: A conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
  • Protein structure: The three-dimensional arrangement of atoms in an amino acid-chain molecule.
  • Protein folding: The physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.
  • Tertiary structure: The overall three-dimensional structure resulting from folding and covalent cross-linking of a protein or polynucleotide molecule.

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