T315I mutation
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T315I mutation | |
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Term | T315I mutation |
Short definition | T315I mutation - type of mutation (change) in the BCR-ABL fusion protein, an abnormal protein that occurs in most people with chronic myeloid leukemia and some with acute lymphoblastic leukemia. The T315I mutation can make cancer cells resistant (unable to respond) to anti-cancer drugs called tyrosine kinase inhibitors. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
T315I mutation - type of mutation (change) in the BCR-ABL fusion protein, an abnormal protein that occurs in most people with chronic myeloid leukemia and some with acute lymphoblastic leukemia. The T315I mutation can make cancer cells resistant (unable to respond) to anti-cancer drugs called tyrosine kinase inhibitors. Checking for the T315I mutation in cancer cells can be helpful in planning cancer treatment
External links
- Medical encyclopedia article on T315I mutation
- Wikipedia's article - T315I mutation
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