TAAR1

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TAAR1

TAAR1 (pronounced "T-A-A-R-1", /tiː eɪ eɪ ɑːr wʌn/), also known as Trace Amine-Associated Receptor 1, is a protein that in humans is encoded by the TAAR1 gene.

Etymology

The term TAAR1 is an acronym derived from "Trace Amine-Associated Receptor 1". The term "trace amine" refers to the group of chemical compounds that are found in the body in trace amounts, and "associated receptor" refers to the protein that these trace amines bind to.

Function

TAAR1 is a high-affinity receptor for amphetamine, methamphetamine, dopamine, and other trace amines. Trace amines are a group of rare endogenous amines that, in concert with their associated receptors, are believed to play a major role in regulation of brain function, especially in the areas of emotion, motivation, and reward.

Related Terms

  • Trace amine: A type of amine that is found in the body in trace amounts.
  • Receptor (biochemistry): A protein molecule that receives chemical signals from outside a cell.
  • Amphetamine: A potent central nervous system stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
  • Dopamine: A type of neurotransmitter – a chemical messenger that transmits signals in the brain and other areas of the body.
  • Methamphetamine: A potent central nervous system stimulant that is mainly used as a recreational drug.

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