Tubulocystic renal cell carcinoma

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Tubulocystic Renal Cell Carcinoma

Tubulocystic renal cell carcinoma (pronounced: too-buh-lo-sis-tik ree-nuhl sel kar-si-noh-muh) is a rare subtype of renal cell carcinoma that is characterized by its unique tubulocystic architecture.

Etymology

The term "tubulocystic" is derived from the Latin words "tubulus" meaning tube and "cysticus" meaning cyst, referring to the tubular and cystic structures observed in this type of carcinoma. "Renal" pertains to the kidneys, from the Latin "renalis". "Cell" is derived from the Latin "cella" meaning a small room, and "carcinoma" is derived from the Greek "karkinos" meaning crab, a term used by Hippocrates to describe tumours because of their crab-like shape and the way they spread throughout the body.

Definition

Tubulocystic renal cell carcinoma is a distinct subtype of renal cell carcinoma that is characterized by its tubulocystic architecture. It is composed of numerous small, tightly packed tubules and cysts lined by a single layer of cuboidal or flattened cells with clear or eosinophilic cytoplasm.

Symptoms

The symptoms of tubulocystic renal cell carcinoma are similar to those of other types of renal cell carcinoma and may include blood in the urine (hematuria), pain in the side or lower back that doesn't go away, loss of appetite, weight loss, and fatigue.

Diagnosis

Diagnosis of tubulocystic renal cell carcinoma is typically made through a combination of imaging studies such as computed tomography (CT) scans or magnetic resonance imaging (MRI), and histopathological examination of a biopsy specimen.

Treatment

Treatment options for tubulocystic renal cell carcinoma may include surgery to remove the tumor, targeted therapy, immunotherapy, or a combination of these treatments.

Prognosis

The prognosis for tubulocystic renal cell carcinoma is generally favorable, with a lower rate of metastasis compared to other subtypes of renal cell carcinoma.

Related Terms

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