Vasoplegic syndrome

Vasoplegic Syndrome

Vasoplegic syndrome (pronunciation: vaso-plej-ic sin-drome) is a medical condition characterized by severe systemic vasodilation, which leads to low systemic vascular resistance and hypotension without a compensatory increase in cardiac output.

Etymology

The term "vasoplegic" is derived from "vaso-", a prefix referring to the vasculature, and "-plegic", a suffix indicating paralysis or immobilization. The syndrome is thus named for its primary characteristic: the inability of the blood vessels to properly constrict, leading to a state of persistent vasodilation.

Symptoms

The primary symptom of vasoplegic syndrome is persistent low blood pressure (hypotension) that does not respond to standard treatments. Other symptoms may include tachycardia (rapid heart rate), oliguria (low urine output), and lactic acidosis (a buildup of lactic acid in the body).

Causes

Vasoplegic syndrome is most commonly associated with cardiac surgery, particularly surgeries involving cardiopulmonary bypass. Other potential causes include sepsis, liver failure, and the use of certain medications, such as vasodilators and calcium channel blockers.

Treatment

Treatment for vasoplegic syndrome typically involves the administration of vasoconstrictors to increase blood pressure. In severe cases, extracorporeal membrane oxygenation (ECMO) may be used to provide cardiac and respiratory support.

Related Terms

External links

Medical encyclopedia article on Vasoplegic syndrome
Wikipedia's article - Vasoplegic syndrome

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Vasoplegic syndrome