Virchow's triad

Virchow's Triad (pronounced: Vir-kow's Try-ad) is a concept that was first proposed by the German pathologist Rudolf Virchow in the 19th century. It refers to the three broad categories of factors that are thought to contribute to the development of thrombosis.

Etymology

The term "Virchow's Triad" is named after Rudolf Virchow, who is often referred to as the "father of modern pathology". He was the first to propose that thrombosis could be caused by multiple factors, which he categorized into three groups.

Components of Virchow's Triad

The three components of Virchow's Triad are:

1. Endothelial Injury: This refers to damage to the endothelium, the thin layer of cells that lines the interior surface of blood vessels. Endothelial injury can be caused by a variety of factors, including trauma, infection, and inflammation.

1. Abnormal Blood Flow: This can refer to any alteration in normal blood flow, including stasis (a state of inactivity or stagnation) or turbulence. Abnormal blood flow can lead to the formation of a thrombus, or blood clot.

1. Hypercoagulability: This refers to an increased tendency of the blood to clot. Hypercoagulability can be caused by a variety of factors, including certain genetic conditions, cancer, and certain medications.

Related Terms

• Thrombosis
• Endothelial Injury
• Abnormal Blood Flow
• Hypercoagulability
• Rudolf Virchow

See Also

• Deep Vein Thrombosis
• Pulmonary Embolism
• Stroke

External links

• Medical encyclopedia article on Virchow's triad
• Wikipedia's article - Virchow's triad

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