Virus inactivation
Virus Inactivation
Virus inactivation (pronunciation: /ˈvʌɪrəs ɪnæktɪˈveɪʃən/) is a process that renders viruses incapable of initiating productive infection. It is a crucial step in the production of viral vaccines and the treatment of viral diseases.
Etymology
The term "virus inactivation" is derived from the Latin virus meaning "poison" or "slime", and the Latin inactivare meaning "to make inactive".
Process
Virus inactivation is achieved through various methods, including Heat treatment, Ultraviolet radiation, Chemical inactivation, and High pressure. These methods disrupt the virus's ability to replicate by damaging its Genetic material or its Protein coat.
Heat Treatment
Heat treatment involves exposing the virus to high temperatures to denature its proteins and nucleic acids, rendering it non-infectious.
Ultraviolet Radiation
Ultraviolet radiation damages the virus's genetic material, preventing it from replicating.
Chemical Inactivation
Chemical inactivation involves the use of chemicals such as Formaldehyde or Beta propiolactone to inactivate the virus.
High Pressure
High pressure can also be used to inactivate viruses, although this method is less commonly used.
Applications
Virus inactivation is used in a variety of applications, including the production of Viral vaccines, the treatment of Blood products, and the sterilization of Medical equipment.
Related Terms
- Virus: A small infectious agent that can only replicate inside the living cells of an organism.
- Inactivation: The process of making something inactive or ineffective.
- Viral inactivation: The process of rendering a virus incapable of initiating productive infection.
External links
- Medical encyclopedia article on Virus inactivation
- Wikipedia's article - Virus inactivation
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