Xanthotoxin
Xanthotoxin
Xanthotoxin (pronounced: zan-tho-tox-in), also known as Methoxsalen, is a furocoumarin and a psoralen derivative. It is a natural product found in several plants of the Apiaceae family, including the Amni majus plant.
Etymology
The term "Xanthotoxin" is derived from the Greek words "xanthos" meaning "yellow" and "toxikon" meaning "poison". This refers to the yellow color of the compound and its toxic properties when exposed to ultraviolet light.
Usage
Xanthotoxin is used in the treatment of psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to sunlight. It works by intercalating the DNA, thus inhibiting DNA synthesis and cell division.
Related Terms
- Furocoumarin: A class of organic chemical compounds produced by a variety of plants.
- Psoralen: A group of natural products that are widely distributed in the plant kingdom.
- Apiaceae: A large family of aromatic flowering plants, commonly known as the celery, carrot or parsley family.
- Amni majus: A plant species in the family Apiaceae, native to the Mediterranean region.
- Psoriasis: A long-lasting autoimmune disease characterized by patches of abnormal skin.
- Eczema: A condition where patches of skin become inflamed, itchy, red, cracked, and rough.
- Vitiligo: A long-term skin condition characterized by patches of the skin losing their pigment.
- Lymphoma: A group of blood malignancies that develop from lymphocytes (a type of white blood cell).
External links
- Medical encyclopedia article on Xanthotoxin
- Wikipedia's article - Xanthotoxin
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