Zydis
Zydis
Zydis (pronounced: /ˈzaɪdɪs/) is a technology used in the pharmaceutical industry to create fast-dissolving formulations of medications. The term "Zydis" is derived from the Greek words "zygos" meaning "yoke" and "dis" meaning "twice", referring to the dual action of the technology in both dissolving the medication and facilitating its absorption.
History
The Zydis technology was developed by the pharmaceutical company Schering-Plough in the 1980s. It was designed to improve the bioavailability of drugs by allowing them to dissolve rapidly in the mouth, without the need for water. This makes it particularly useful for patients who have difficulty swallowing tablets or capsules.
How it Works
Zydis technology involves the production of a porous, fast-dissolving tablet that disintegrates on contact with saliva within seconds. The active drug is incorporated into a matrix using a freeze-drying process. This results in a product that is stable, convenient to use, and can deliver the drug rapidly and efficiently.
Applications
Zydis technology has been used to formulate a variety of medications, including antipsychotics, antihistamines, and analgesics. It is particularly useful for drugs that are poorly soluble or have a bitter taste, as the rapid dissolution of the tablet can reduce the exposure of the drug to the taste buds.
Related Terms
- Orally disintegrating tablet: A type of tablet that dissolves in the mouth rather than being swallowed whole.
- Bioavailability: The proportion of a drug that enters the circulation when introduced into the body and so is able to have an active effect.
- Pharmaceutical formulation: The process in which different chemical substances, including the active drug, are combined to produce a final medicinal product.
External links
- Medical encyclopedia article on Zydis
- Wikipedia's article - Zydis
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski