(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid is a chemical compound that acts as a selective antagonist of the GABAC receptor. It is commonly abbreviated as TPMPA.
Chemical Structure
The chemical structure of (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid consists of a tetrahydropyridine ring attached to a methylphosphinic acid group. The presence of the phosphinic acid moiety is crucial for its activity as a GABAC receptor antagonist.
Mechanism of Action
TPMPA functions by selectively inhibiting the GABAC receptors, which are a subclass of GABA receptors. These receptors are ligand-gated ion channels that mediate inhibitory neurotransmission in the central nervous system. By blocking these receptors, TPMPA can modulate the inhibitory effects of GABA, potentially affecting various neurological processes.
Applications in Research
Due to its selective antagonistic properties, TPMPA is used in neuroscience research to study the role of GABAC receptors in the brain. It helps in understanding the physiological and pathological roles of these receptors in various neurological conditions.
Related Compounds
TPMPA is part of a broader class of compounds known as GABA receptor antagonists. Other related compounds include bicuculline and picrotoxin, which target different subtypes of GABA receptors.
See Also
Related Pages
Structure of (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
