2-MAPB

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Overview

Chemical structure of 2-MAPB

2-MAPB (2-Methylamino-1-phenylbutane) is a synthetic compound that belongs to the class of phenethylamines. It is structurally related to other psychoactive substances such as amphetamine and methamphetamine. 2-MAPB is known for its stimulant and entactogenic effects, which are similar to those of MDMA (3,4-methylenedioxy-N-methylamphetamine).

Chemical Properties

2-MAPB is a phenethylamine derivative with the chemical formula C11H17N. It features a phenyl ring bonded to an amino group via a butane chain. The presence of a methyl group attached to the nitrogen atom distinguishes it from other related compounds. This structural modification influences its pharmacological activity and metabolic stability.

Pharmacology

2-MAPB acts primarily as a serotonin and dopamine releasing agent. It increases the levels of these neurotransmitters in the brain, leading to its psychoactive effects. The compound's action on the serotonin system is responsible for its mood-enhancing and empathogenic properties, while its effect on dopamine contributes to its stimulant characteristics.

Effects

The effects of 2-MAPB are reported to be similar to those of MDMA, including increased sociability, empathy, and euphoria. Users may also experience enhanced sensory perception and a heightened sense of well-being. However, like other stimulants, it can also cause adverse effects such as increased heart rate, anxiety, and insomnia.

Legal Status

The legal status of 2-MAPB varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. In others, it may be available as a research chemical, though its sale and distribution are often subject to regulation.

Related Compounds

2-MAPB is part of a broader class of compounds known as substituted amphetamines. Other related compounds include:

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Contributors: Prab R. Tumpati, MD