Analgesic adjuvant
Analgesic adjuvants are drugs that are not primarily designed to control pain but can be used for this purpose. They are often used in combination with analgesics to enhance their effects or to alleviate side effects.
Types of Analgesic Adjuvants
There are several types of analgesic adjuvants, including:
- Antidepressants: These are often used to treat neuropathic pain. They work by increasing the levels of certain chemicals in the brain that help reduce the perception of pain.
- Anticonvulsants: These are used to treat neuropathic pain and fibromyalgia. They work by reducing the excitability of nerve cells, which can help reduce pain.
- Corticosteroids: These are used to reduce inflammation and swelling, which can help reduce pain.
- Muscle relaxants: These are used to treat muscle spasms and tension, which can cause pain.
- Benzodiazepines: These are used to treat anxiety and muscle spasms, which can contribute to pain.
Uses of Analgesic Adjuvants
Analgesic adjuvants are used in a variety of situations, including:
- To enhance the effects of analgesics
- To treat pain that is not adequately controlled by analgesics alone
- To reduce the side effects of analgesics
- To treat specific types of pain, such as neuropathic pain or fibromyalgia
Side Effects of Analgesic Adjuvants
Like all drugs, analgesic adjuvants can have side effects. These can vary depending on the specific drug and the individual patient, but may include:
- Drowsiness
- Dizziness
- Nausea
- Constipation
- Dry mouth
- Changes in appetite or weight
- Difficulty sleeping
Patients should discuss potential side effects with their healthcare provider before starting treatment with an analgesic adjuvant.
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Contributors: Prab R. Tumpati, MD