Apoenzyme
Apoenzyme
Apoenzyme (/ˌæpoʊˈɛnzaɪm/), also known as an apoprotein, is the protein component of an enzyme, which requires a cofactor to be functional. It is, in essence, an inactive enzyme without its necessary non-protein component.
Etymology
The term "apoenzyme" is derived from the Greek words "apo", meaning "away from", and "enzyme", which is itself derived from "en zyme", meaning "in yeast". The term thus essentially means "the enzyme away from its cofactor".
Related Terms
- Cofactor: A non-protein chemical compound or metallic ion that is required for an enzyme's activity as a catalyst (a substance that increases the rate of a chemical reaction).
- Holoenzyme: The active form of an enzyme, including all its subunits and cofactors.
- Prosthetic group: A tightly bound, specific non-polypeptide unit required for the biological function of some proteins.
- Enzyme: A protein that acts as a biological catalyst.
See Also
External links
- Medical encyclopedia article on Apoenzyme
- Wikipedia's article - Apoenzyme
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