Atracurium
Atracurium (pronounced: a-tra-KYUR-ee-um) is a non-depolarizing skeletal muscle relaxant used in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Etymology
The term "Atracurium" is derived from its chemical structure, which is a bisquaternary ammonium compound. The prefix "Atra-" is derived from Latin, meaning "dark" or "black", and "curium" is derived from the Latin word "curare", which means "to care for". This is in reference to its use in medical procedures to provide muscle relaxation and facilitate care.
Pharmacology
Atracurium works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system to contract muscles. It is a non-depolarizing agent, meaning it does not cause the muscles to contract before they relax. Instead, it simply prevents acetylcholine from binding to its receptors, thereby preventing muscle contraction.
Usage
Atracurium is used in a clinical setting, primarily during surgical procedures and in intensive care units. It is administered intravenously and its effects are usually noticeable within 2-3 minutes of administration. The duration of its effects can last up to 45 minutes, and it is typically used in conjunction with other anesthetic agents.
Related Terms
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