Bardoxolone
Bardoxolone
Bardoxolone (pronounced: bar-dox-oh-lone) is a synthetic triterpenoid that has been investigated for its potential therapeutic effects in various medical conditions.
Etymology
The term "Bardoxolone" is derived from the chemical name "2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid". The name is often abbreviated as "BARD" or "CDDO".
Usage
Bardoxolone has been studied for its potential use in the treatment of chronic kidney disease (CKD) and pulmonary hypertension. It is believed to work by reducing inflammation and oxidative stress, two factors that contribute to the progression of these diseases.
Related Terms
- Triterpenoid: A type of chemical compound that is the basis for the structure of Bardoxolone.
- Chronic kidney disease: A long-term condition that Bardoxolone has been investigated for its potential to treat.
- Pulmonary hypertension: A type of high blood pressure that affects the arteries in the lungs and the right side of the heart. Bardoxolone has been studied for its potential use in treating this condition.
- Inflammation: A biological response to harmful stimuli, such as pathogens, damaged cells, or irritants. Bardoxolone is believed to work by reducing inflammation.
- Oxidative stress: An imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects. Bardoxolone is thought to work by reducing oxidative stress.
See Also
- Reata Pharmaceuticals: The company that developed Bardoxolone.
- Antioxidant: A substance that reduces oxidative stress, a proposed mechanism of action for Bardoxolone.
External links
- Medical encyclopedia article on Bardoxolone
- Wikipedia's article - Bardoxolone
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