Benoxaprofen
Benoxaprofen
Benoxaprofen (/bɛnɒksəˈprɒfɛn/), also known as Oraflex in the United States and as Opren in the United Kingdom, is a nonsteroidal anti-inflammatory drug (NSAID) that was withdrawn from the market due to its adverse side effects.
Etymology
The name "Benoxaprofen" is derived from the chemical structure of the drug, which is a derivative of benzoxazole and propionic acid.
Pharmacology
Benoxaprofen is a type of nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. It was used to treat rheumatoid arthritis and osteoarthritis.
History
Benoxaprofen was developed by Eli Lilly and Company and was first approved for use in the United Kingdom in 1980. It was later approved in the United States in 1982. However, it was withdrawn from the market in both countries later that year due to reports of serious side effects, including liver damage and death.
Side Effects
The side effects of Benoxaprofen include gastrointestinal bleeding, kidney failure, and liver damage. It was withdrawn from the market due to these serious side effects.
Related Terms
- Nonsteroidal anti-inflammatory drug
- Prostaglandins
- Rheumatoid arthritis
- Osteoarthritis
- Eli Lilly and Company
- Gastrointestinal bleeding
- Kidney failure
- Liver damage
External links
- Medical encyclopedia article on Benoxaprofen
- Wikipedia's article - Benoxaprofen
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