Benzbromarone
Benzbromarone (pronounced: ben-zbro-mar-one) is a medication used primarily for the treatment of gout. It belongs to the class of drugs known as uricosuric agents, which work by increasing the excretion of uric acid in the urine, thereby reducing the concentration of uric acid in the body.
Etymology
The name "Benzbromarone" is derived from the chemical structure of the drug, which contains a benzene ring (benz-), a bromine atom (brom-), and a ketone group (-arone).
Pharmacology
Benzbromarone acts by inhibiting the enzyme uric acid transporter 1 (URAT1), which is responsible for the reabsorption of uric acid in the kidneys. By blocking this transporter, Benzbromarone increases the excretion of uric acid in the urine, thereby reducing its concentration in the body.
Clinical Use
Benzbromarone is used primarily for the treatment of chronic gout, a condition characterized by high levels of uric acid in the blood, which can lead to the formation of uric acid crystals in the joints, causing pain and inflammation. It is also used in the treatment of hyperuricemia, a condition characterized by abnormally high levels of uric acid in the blood.
Side Effects
Like all medications, Benzbromarone can cause side effects. The most common side effects include gastrointestinal disturbances, such as nausea and diarrhea, and skin rashes. In rare cases, it can cause serious liver damage.
See Also
External links
- Medical encyclopedia article on Benzbromarone
- Wikipedia's article - Benzbromarone
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