Berliner
Berliner
Berliner (pronunciation: /bɛrˈliːnər/) is a term with multiple meanings, depending on the context. In the medical field, it is often associated with the Berliner Blau reaction, a histochemical reaction used in pathology.
Etymology
The term "Berliner" is derived from the city of Berlin, Germany. The Berliner Blau reaction was first developed in Berlin, hence the name.
Berliner Blau Reaction
The Berliner Blau Reaction is a histochemical reaction used to detect the presence of ferric iron in tissue samples. It is also known as the Perls' Prussian Blue Reaction, named after the German pathologist Max Perls.
Procedure
The procedure involves treating the tissue sample with a mixture of hydrochloric acid and potassium ferrocyanide. This results in the formation of a bright blue pigment, known as Prussian blue, in areas where ferric iron is present.
Applications
The Berliner Blau reaction is primarily used in the diagnosis of diseases such as hemochromatosis and hemosiderosis, which are characterized by excessive iron accumulation in the body.
Related Terms
- Histochemistry: The study of the chemical composition of cells and tissues.
- Ferric Iron: A form of iron present in the body.
- Hemochromatosis: A genetic disorder characterized by excessive iron absorption.
- Hemosiderosis: A condition characterized by the accumulation of hemosiderin, an iron-storage complex, in the body.
External links
- Medical encyclopedia article on Berliner
- Wikipedia's article - Berliner
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