Burkholderia multivorans

Burkholderia multivorans is a bacterial species belonging to the genus Burkholderia. It is a Gram-negative, aerobic, rod-shaped bacterium that is commonly found in the soil and water. B. multivorans is known for its ability to degrade a wide range of organic compounds, hence the name multivorans which means "many foods".

Characteristics

Burkholderia multivorans is a motile bacterium, possessing flagella that allow it to move in liquid environments. It is also capsulated, which provides it with protection against desiccation and antibiotics. The bacterium is oxidase positive and can grow in a temperature range of 20-40°C.

Pathogenicity

Burkholderia multivorans is an opportunistic pathogen, meaning it can cause disease in individuals with compromised immune systems. It is one of the most common Burkholderia species found in patients with cystic fibrosis, where it can cause chronic lung infections. The bacterium is also associated with granulomatous diseases and sepsis.

Treatment

Treatment of Burkholderia multivorans infections can be challenging due to the bacterium's inherent resistance to many commonly used antibiotics. Antibiotic susceptibility testing is often required to determine the most effective treatment strategy.

Research

Research into Burkholderia multivorans is ongoing, with studies focusing on its pathogenicity, antibiotic resistance mechanisms, and potential uses in bioremediation due to its ability to degrade a wide range of organic compounds.

See also

• Burkholderia cepacia complex
• Opportunistic infection
• Cystic fibrosis