CGMP
CGMP
CGMP (pronounced "see-GMP") is an acronym for Cyclic Guanosine Monophosphate. It is a cyclic nucleotide derived from guanosine triphosphate (GTP).
Etymology
The term CGMP is derived from its full name, Cyclic Guanosine Monophosphate. The "C" stands for Cyclic, referring to the cyclic nature of the molecule. "Guanosine" is derived from guanine, one of the four main nucleobases found in the nucleic acids DNA and RNA. "Monophosphate" refers to the presence of a single phosphate group in the molecule.
Function
CGMP acts as a second messenger, much like cyclic AMP. Its most likely mechanism of action is activation of intracellular protein kinases in response to the binding of membrane-impermeable peptide hormones to the external cell surface.
Related Terms
- Guanosine Triphosphate (GTP): The molecule from which CGMP is derived.
- Cyclic AMP (cAMP): Another second messenger that functions similarly to CGMP.
- Protein Kinase: An enzyme that CGMP activates.
- Peptide Hormone: A type of hormone that can trigger CGMP production.
See Also
External links
- Medical encyclopedia article on CGMP
- Wikipedia's article - CGMP
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