Canalicular adenoma

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Canalicular Adenoma

Canalicular adenoma (kəˌnælɪˈkjʊlər ædɪˈnoʊmə) is a benign neoplasm that primarily affects the salivary glands. The term "canalicular" is derived from the Latin word "canaliculus," meaning "small canal," and "adenoma" from the Greek words "aden," meaning "gland," and "-oma," meaning "tumor."

Definition

Canalicular adenoma is a rare, benign tumor that originates from the intercalated duct cells of the salivary glands. It is characterized by a monomorphic proliferation of small, columnar, or cuboidal epithelial cells arranged in a canalicular pattern.

Epidemiology

Canalicular adenomas account for approximately 1% of all salivary gland tumors. They are most commonly found in the upper lip and buccal mucosa, but can also occur in the palate and other minor salivary glands. These tumors are more common in older adults, with a peak incidence in the seventh decade of life. There is a slight female predilection.

Clinical Presentation

Patients with canalicular adenoma typically present with a slow-growing, painless mass in the upper lip or buccal mucosa. The mass is usually less than 2 cm in diameter and is often mistaken for a mucocele or fibroma.

Diagnosis

The diagnosis of canalicular adenoma is typically made based on histopathological examination of the tumor. The tumor is composed of uniform, small, columnar or cuboidal cells arranged in a canalicular pattern. The cells have eosinophilic cytoplasm and round to oval nuclei. The stroma is typically fibrous and may contain foci of calcification.

Treatment

The treatment of choice for canalicular adenoma is surgical excision. Recurrence is rare, but can occur if the tumor is not completely removed.

Prognosis

The prognosis for canalicular adenoma is excellent, as these tumors are benign and do not metastasize. However, recurrence can occur if the tumor is not completely excised.

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