Carr index
Carr Index
The Carr Index (pronounced: /kɑːr ˈɪndɛks/), also known as the Carr's Compressibility Index, is a measure used in pharmaceutics to predict the packing behavior and flowability of powders and granules. The term is named after Ralph J. Carr, who first introduced the concept.
Etymology
The term "Carr Index" is derived from the name of Ralph J. Carr, a renowned pharmacist who first proposed this measure. The word "index" is derived from the Latin word 'indicare', meaning to indicate or point out, reflecting the function of the Carr Index as an indicator of powder flowability.
Definition
The Carr Index is calculated as the difference between the bulk density (ρb) and tapped density (ρt) of the powder, divided by the tapped density, multiplied by 100. The result is expressed as a percentage.
Carr Index (%) = ((ρt - ρb) / ρt) * 100
Related Terms
- Bulk Density: The mass of powder divided by its bulk volume.
- Tapped Density: The density of a powder after it has been tapped or vibrated, which increases its density.
- Hausner Ratio: Another measure of the flowability of a powder, closely related to the Carr Index.
- Pharmaceutics: The discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) or old drugs into a medication to be used safely and effectively by patients.
See Also
External links
- Medical encyclopedia article on Carr index
- Wikipedia's article - Carr index
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