Cholestatic pruritus
Cholestatic Pruritus
Cholestatic pruritus (pronounced: koh-lee-stat-ik proo-ri-tus) is a type of itching that occurs in some patients with liver disease. It is specifically associated with cholestasis, a condition where bile cannot flow from the liver to the duodenum.
Etymology
The term "cholestatic pruritus" is derived from two words. "Cholestatic" comes from the Greek words "chole" meaning "bile" and "stasis" meaning "standing still". "Pruritus" is a Latin word which means "itching".
Symptoms
The main symptom of cholestatic pruritus is intense itching. This itching is often worse at night and may be widespread or localized. Other symptoms may include jaundice, dark urine, and pale stools.
Causes
Cholestatic pruritus is caused by a buildup of bile acids in the skin due to cholestasis. This can occur in various liver diseases such as primary biliary cirrhosis, primary sclerosing cholangitis, and hepatitis.
Treatment
Treatment for cholestatic pruritus aims to reduce the levels of bile acids in the body. This can be achieved through medication, such as ursodeoxycholic acid, or through procedures like plasmapheresis.
Related Terms
External links
- Medical encyclopedia article on Cholestatic pruritus
- Wikipedia's article - Cholestatic pruritus
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