Cioteronel
Cioteronel
Cioteronel (pronounced: /siːoʊtɛrənɛl/) is a non-steroidal antiandrogen that was never marketed. It is a thiohydantoin derivative and is structurally related to nilutamide, which is a drug that is used in the treatment of prostate cancer.
Etymology
The term "Cioteronel" is derived from the chemical name Cyclohexylmethyl Isoxazole Oxime Thiohydantoin Ethanol, with the suffix "-ronel" added for ease of pronunciation.
Pharmacology
Cioteronel works by blocking the effects of androgens like testosterone in the body. It does this by binding to the androgen receptors in the cells, preventing the androgens from binding and exerting their effects. This can help to slow the growth of certain types of cancer cells that need androgens to grow, such as prostate cancer cells.
Related Terms
- Antiandrogen: A substance that inhibits the biological effects of androgen hormones in the body.
- Androgen: A type of hormone that plays a role in male traits and reproductive activity.
- Testosterone: The primary sex hormone and anabolic steroid in males.
- Prostate Cancer: A type of cancer that occurs in the prostate — a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm.
- Nilutamide: An antiandrogen which is used in the treatment of prostate cancer.
External links
- Medical encyclopedia article on Cioteronel
- Wikipedia's article - Cioteronel
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