Classic familial polyposis

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Classic familial polyposis
TermClassic familial polyposis
Short definitionclassic familial polyposis - (pronounced) (KLA-sik fuh-MIH-lee-ul PAH-lee-POH-sis) An inherited disorder in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


classic familial polyposis - (pronounced) (KLA-sik fuh-MIH-lee-ul PAH-lee-POH-sis) An inherited disorder in which many polyps (usually hundreds to thousands) form on the inner walls of the colon and rectum. Polyps are abnormal growths that can become cancer if not removed. People with classic familial polyposis have a very high risk of developing colon cancer early on, and also have an increased risk of developing cancers of the stomach, small intestine, pancreas, bile duct, liver, adrenal gland, thyroid, and brain. They can also have dental and eye problems, and benign (noncancerous) tumors in the stomach, small intestine, bones, soft tissues, skin, and adrenal glands. Classic familial polyposis is caused by mutations (changes) in a so-called geneAPCwhich are inherited in an autosomal dominant manner. It's a kind of hereditary cancer syndrome. Also called classic familial adenomatous polyposis, classic FAP, familial adenomatous polyposis and FAP

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