Clofazimine
Clofazimine
Clofazimine (pronounced klo-FAZ-uh-meen) is a medication used primarily in the treatment of leprosy. It is part of the World Health Organization's List of Essential Medicines, indicating its critical importance in the health system.
Etymology
The term "Clofazimine" is derived from the chemical name clorofanylazozine.
Usage
Clofazimine is used in combination with other antibacterial agents to treat leprosy, a chronic infectious disease caused by Mycobacterium leprae. It is also used off-label for a variety of other conditions, including Mycobacterium avium complex (MAC) disease and Crohn's disease.
Mechanism of Action
Clofazimine works by binding to the DNA of bacteria, disrupting their growth and reproduction. It also has anti-inflammatory properties that help reduce the symptoms of leprosy.
Side Effects
Common side effects of clofazimine include skin discoloration, dry skin, and gastrointestinal discomfort. More serious side effects may include eye damage and severe abdominal pain.
Related Terms
External links
- Medical encyclopedia article on Clofazimine
- Wikipedia's article - Clofazimine
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