Coats' disease

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Coats' Disease

Coats' Disease (pronounced: /koʊts diːz/), also known as Coats Syndrome or exudative retinitis, is a rare eye disorder characterized by abnormal development of the blood vessels in the retina. The disease was first described by the British ophthalmologist George Coats in 1908.

Etymology

The disease is named after George Coats, a British ophthalmologist who first described the condition in 1908.

Symptoms

The symptoms of Coats' Disease can vary greatly from person to person. However, common symptoms include vision loss, leukocoria (a white reflection in the pupil), strabismus (misalignment of the eyes), and glaucoma (increased pressure in the eye).

Causes

The exact cause of Coats' Disease is unknown. However, it is believed to be caused by a mutation in the Norrie disease gene. This gene is responsible for the production of a protein that plays a crucial role in the development of the eye.

Diagnosis

Diagnosis of Coats' Disease is typically made through a comprehensive eye examination. This may include a fundus examination, optical coherence tomography (OCT), and fluorescein angiography.

Treatment

Treatment for Coats' Disease typically involves surgery to remove the abnormal blood vessels. This may be done through laser photocoagulation, cryotherapy, or vitrectomy. In severe cases, the entire eye may need to be removed (enucleation).

Prognosis

The prognosis for Coats' Disease varies greatly depending on the severity of the disease and the age at which it is diagnosed. Early detection and treatment can significantly improve the prognosis.

See Also

External links

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