Crotonylfentanyl
Crotonylfentanyl is a potent opioid analgesic that is an analog of fentanyl. It is a designer drug and has been sold online as a research chemical. It is a member of the fentanyl series of drugs and has similar effects.
Chemistry
Crotonylfentanyl is a fentanyl analog, more specifically a 4-anilidopiperidine derivative. It is named for the crotonyl group that is attached to the nitrogen atom in the piperidine ring. The chemical formula of crotonylfentanyl is C24H30N2O2.
Pharmacology
Like other opioids, crotonylfentanyl acts on the mu-opioid receptor to produce its analgesic effects. It is significantly more potent than morphine. The exact potency of crotonylfentanyl is not known, but it is likely to be similar to that of other potent fentanyl analogs.
Effects
The effects of crotonylfentanyl are similar to those of other opioids and include analgesia, sedation, euphoria, constipation, itching and respiratory depression which can be harmful or fatal.
Legal Status
Crotonylfentanyl is a controlled substance in several countries, including the United States, where it is a Schedule I drug under the Controlled Substances Act. It is also controlled in China and several European countries.
Health Risks
As with other opioids, the use of crotonylfentanyl carries a risk of addiction, dependence, and withdrawal. Overdose can result in severe respiratory depression or death.
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Contributors: Prab R. Tumpati, MD