Crowe sign
Crowe sign (pronunciation: /kroʊ saɪn/) is a medical term used to describe a specific symptom often associated with Neurofibromatosis Type 1 (NF1).
Etymology
The term is named after Frederick Parkes Weber and John W. Crowe, who first described the sign in patients with NF1.
Definition
Crowe sign is characterized by the presence of freckling in the axilla (armpit) or the inguinal region (groin). This sign is considered a diagnostic criterion for NF1, a genetic disorder that causes tumors to form on nerve tissue.
Related Terms
- Neurofibromatosis: A genetic disorder that causes tumors to form on nerve tissue. These tumors can develop anywhere in the nervous system, including the brain, spinal cord, and nerves.
- Axilla: The armpit, or the cavity beneath the junction of the arm and body.
- Inguinal region: The lower lateral regions of the abdomen, located on either side of the pubic area, extending from the pubes to the iliac crest.
- Freckling: Small, flat, brown marks appearing on the skin.
See Also
External links
- Medical encyclopedia article on Crowe sign
- Wikipedia's article - Crowe sign
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